Extraction of hyaluronic acid from rabbit skin with lanthanum chloride.

An Extraction Study of Gallium and Indium from Chloride and Sulphate Media with Sec-Nonylphenoxy Acetic Acid in Kerosene

The distribution of gallium(b) and indium (b) between hydrochloric or sulphuric acid solution with sec-nonylphenoxy acetic acid(CA-100) in kerosene has been investigated under various conditions. CA-100 is a new organocarboxylic extractant, which has been shown to be efficient for gallium(b) and indium(b) where...

Hyaluronic Acid, Mesotherapy and Skin Rejuvenation

Injectable hyaluronic-acid-doxycycline hydrogel therapy in experimental rabbit osteoarthritis

BACKGROUND Osteoarthritis (OA) is a common joint disease that causes disabilities in elderly adults. However, few long-lasting pharmacotherapeutic agents with low side effects have been developed to treat OA. We evaluated the therapeutic effects of intra-articular injections of hydrogels containing hyaluronic acid (HA) and doxycycline (DOX) in a rabbit OA model. RESULTS Thirteen week old New ...

Isolation and physical characterization of hyaluronic acid prepared from bovine nasal septum by cetylpyridinium chloride precipitation.

Raw extract in 2 m CaCl2 of bovine nasal septum cartilage was eluted from 4 per cent agarose gel to give a "void volume" Fraction v-4, which was indistinguishable in composition and behavior on viscometric and sedimentation analysis from the densest fraction obtained by associative centrifugation in a cesium chloride density gradient. The sulfated proteoglycan was precipitated (Fraction A) by c...

Pulsed current iontophoresis of hyaluronic acid in living rat skin.

Hyaluronic acid (HA) is a natural glycosaminoglycan (GAG) used in treatment and prevention of different skin diseases and as a filler agent for improving wrinkles, scars, or increasing volumes [1]. Because of chemical structure, HA has to be injected repeatedly for many months [2], in tens or hundreds of sites [3], by experienced operators [4]. This feature contrasts with the needs of today’s b...